Gene Ontology Help

GINS complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Required for the initiation of replication and for replication fork progression, mediating interactions with replication factors. Binds to and enhances the enzymatic function of the MCM helicase (CPX-2944) during the initiation and elongation stages of replication. Core component of the replicative helicase CMG (CPX-297) complex that serves as the replicative helicase unwinding duplex DNA ahead of moving replication fork during chromosome duplication. Also appears to interact with and stimulate the polymerase activities of DNA polymerase epsilon complex (CPX-2110) and the DNA polymerase alpha:primase complex (CPX-2091).
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

DNA binding, chromosome organization, regulation of DNA metabolic process, nucleus, organelle