Gene Ontology Help

ERMES complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
The ERMES complex serves as a physical connection between the endoplasmic reticulum (ER) and the mitochondrion. The complex, or simply the physical connection provided by the complex, may facilitate transfer of lipids, calcium ions, or other metabolites between the organelles. Mitochondrial nucleoids are located near ERMES, and the complex is required for accurate segregation of the mitochondrial genome. Mutations is any of the complex subunit genes confer aberrant mitochondrial morphology and inheritance.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

protein-macromolecule adaptor activity, homeostatic process, mitochondrion organization