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    Gene Ontology Term: R2TP complex


    GO ID
    GO:0097255
    Aspect
    Cellular Component
    Description
    A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others.
    View GO Annotations in other species in AmiGO

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    Manually Curated

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    Evidence ID Analyze ID Gene/Complex Systematic Name/Complex Accession Qualifier Gene Ontology Term ID Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
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    High-throughput

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    Evidence ID Analyze ID Gene/Complex Systematic Name/Complex Accession Qualifier Gene Ontology Term ID Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
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    Computational

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    Evidence ID Analyze ID Gene/Complex Systematic Name/Complex Accession Qualifier Gene Ontology Term ID Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
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