Gene Ontology Help

Glycine decarboxylase multienzyme complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Catalyzes the oxidative cleavage of glycine into CO2 and NH3, utimately playing a role in the conversion of glycine to serine. The concomitant transfer of a methylene carbon unit to THF1 generates the C1 donor 5,10-methylene tetrahydrofolate. Located in the mitochondrion. The P protein (GCV2, P49095) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GV3, P39726).
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

oxidoreductase activity, transferase activity, amino acid metabolic process, catabolic process, small molecule metabolic process, mitochondrion, organelle