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Gene Ontology Help

TIM9-TIM10 mitochondrial intermembrane space protein transporter complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.

Summary
Facilitates transport of hydrophobic precursors of a distinct subgroup of inner membrane proteins through the aqueous intermembrane space as they exit the TOM40 channel complex (CPX-474) in the outer membrane. Functions as a chaperone to maintain the hydrophobic membrane proteins in an import competent state and escort substrates to the TIM22 insertion complex (CPX-1629), which mediates protein insertion into the membrane.. Cross-links to the COOH-terminal domain of the essential import translocase protein TIM23 (P32897) and plays a key role in TIM23 import to the mitochondrial inner membrane.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

membrane organization, mitochondrion organization, transport

Biological Process

Manually curated GO annotations reflect our best understanding of the basic biological process for this protein complex. Manually curated annotations are assigned by curators based on published papers when available, or by curatorial statements if necessary. Curators periodically review all manually curated GO annotations for accuracy and completeness.

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Qualifier Gene Ontology Term Annotation Extension Evidence Source Assigned On Reference

Shared Annotations

This diagram displays Gene Ontology terms (green) that are shared between the given macromolecular complex (black) and other yeast complexes (yellow). Note: No diagram is shown ("No shared annotations") if there are less than 2 shared GO annotations between this complex and any other complexes.