Gene Ontology Help

PCL2-PHO85 kinase complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Cyclin-dependent protein kinase essential for the control of the cell cycle at the G1/S (start) transition. Phosphorylates RVS167 which functions in actin cytoskeleton regulation and is required for the formation of endocytic vesicles at the plasma membrane. Positively controls degradation of sphingoid long chain base kinase LCB4 (Q12246) by phosphorylation, which is required for its ubiquitination and degradation. LCB4 catalyses the formation of sphingoid long-chain base 1-phosphates which have roles in roles in heat stress resistance, diauxic shift, and Ca2+ mobilization.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

kinase activity, transferase activity, cytoskeleton organization, lipid metabolic process, monocarboxylic acid metabolic process, small molecule metabolic process, site of polarized growth