Primary Literature
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- Reusswig KU, et al. (2022) Unscheduled DNA replication in G1 causes genome instability and damage signatures indicative of replication collisions. Nat Commun 13(1):7014 PMID: 36400763
- Salay LE, et al. (2022) Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase. Biochemistry 61(11):1113-1123 PMID: 35617695
- Kassube SA and Thomä NH (2020) Structural insights into Fe-S protein biogenesis by the CIA targeting complex. Nat Struct Mol Biol 27(8):735-742 PMID: 32632277
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- Porcella SY, et al. (2020) Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongation. PLoS Genet 16(5):e1008755 PMID: 32379761
- Yuan Z, et al. (2019) Ctf4 organizes sister replisomes and Pol α into a replication factory. Elife 8 PMID: 31589141
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- O'Brien E, et al. (2018) Yeast require redox switching in DNA primase. Proc Natl Acad Sci U S A 115(52):13186-13191 PMID: 30541886
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- Perez-Arnaiz P, et al. (2017) An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-α to Mcm2-7. Nucleic Acids Res 45(12):7261-7275 PMID: 28510759
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- Ramachandran A, et al. (2016) The Yeast Mitochondrial RNA Polymerase and Transcription Factor Complex Catalyzes Efficient Priming of DNA Synthesis on Single-stranded DNA. J Biol Chem 291(32):16828-39 PMID: 27311715
- Rice C and Skordalakes E (2016) Structure and function of the telomeric CST complex. Comput Struct Biotechnol J 14:161-7 PMID: 27239262
- Dubarry M, et al. (2015) Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae. G3 (Bethesda) 5(10):2187-97 PMID: 26297725
- Liu L and Huang M (2015) Essential role of the iron-sulfur cluster binding domain of the primase regulatory subunit Pri2 in DNA replication initiation. Protein Cell 6(3):194-210 PMID: 25645023
- Stuckey R, et al. (2015) Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system. Proc Natl Acad Sci U S A 112(18):5779-84 PMID: 25902524
- Sun J, et al. (2015) The architecture of a eukaryotic replisome. Nat Struct Mol Biol 22(12):976-82 PMID: 26524492
- Suwa Y, et al. (2015) Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit. J Biol Chem 290(23):14328-37 PMID: 25847248
- Doublié S and Zahn KE (2014) Structural insights into eukaryotic DNA replication. Front Microbiol 5:444 PMID: 25202305
- Langston LD, et al. (2014) CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication. Proc Natl Acad Sci U S A 111(43):15390-5 PMID: 25313033
- Vaithiyalingam S, et al. (2014) Insights into eukaryotic primer synthesis from structures of the p48 subunit of human DNA primase. J Mol Biol 426(3):558-69 PMID: 24239947
- Perera RL, et al. (2013) Mechanism for priming DNA synthesis by yeast DNA polymerase α. Elife 2:e00482 PMID: 23599895
- Aves SJ, et al. (2012) Evolutionary diversification of eukaryotic DNA replication machinery. Subcell Biochem 62:19-35 PMID: 22918578
- Kilkenny ML, et al. (2012) A conserved motif in the C-terminal tail of DNA polymerase α tethers primase to the eukaryotic replisome. J Biol Chem 287(28):23740-7 PMID: 22593576
- Suyari O, et al. (2012) Differential requirement for the N-terminal catalytic domain of the DNA polymerase ε p255 subunit in the mitotic cell cycle and the endocycle. Gene 495(2):104-14 PMID: 22245183
- Núñez-RamÃrez R, et al. (2011) Flexible tethering of primase and DNA Pol α in the eukaryotic primosome. Nucleic Acids Res 39(18):8187-99 PMID: 21715379
- Zheng L and Shen B (2011) Okazaki fragment maturation: nucleases take centre stage. J Mol Cell Biol 3(1):23-30 PMID: 21278448
- MacNeill SA (2010) Structure and function of the GINS complex, a key component of the eukaryotic replisome. Biochem J 425(3):489-500 PMID: 20070258
- Sauguet L, et al. (2010) Shared active site architecture between the large subunit of eukaryotic primase and DNA photolyase. PLoS One 5(4):e10083 PMID: 20404922
- Tanaka H, et al. (2009) Ctf4 coordinates the progression of helicase and DNA polymerase alpha. Genes Cells 14(7):807-20 PMID: 19496828
- Kim JM, et al. (2008) A copula method for modeling directional dependence of genes. BMC Bioinformatics 9:225 PMID: 18447957
- Klinge S, et al. (2007) An iron-sulfur domain of the eukaryotic primase is essential for RNA primer synthesis. Nat Struct Mol Biol 14(9):875-7 PMID: 17704817
- Lydeard JR, et al. (2007) Break-induced replication and telomerase-independent telomere maintenance require Pol32. Nature 448(7155):820-3 PMID: 17671506
- Das-Bradoo S, et al. (2006) Interaction between PCNA and diubiquitinated Mcm10 is essential for cell growth in budding yeast. Mol Cell Biol 26(13):4806-17 PMID: 16782870
- Petreaca RC, et al. (2006) Chromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p. Nat Cell Biol 8(7):748-55 PMID: 16767082
- Ricke RM and Bielinsky AK (2006) A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast. J Biol Chem 281(27):18414-25 PMID: 16675460
- Nedelcheva MN, et al. (2005) Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex. J Mol Biol 347(3):509-21 PMID: 15755447
- Early A, et al. (2004) Mechanisms involved in regulating DNA replication origins during the cell cycle and in response to DNA damage. Philos Trans R Soc Lond B Biol Sci 359(1441):31-8 PMID: 15065654
- Fien K, et al. (2004) Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. J Biol Chem 279(16):16144-53 PMID: 14766746
- Grossi S, et al. (2004) Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation. Genes Dev 18(9):992-1006 PMID: 15132993
- Sundin BA, et al. (2004) Localization of proteins that are coordinately expressed with Cln2 during the cell cycle. Yeast 21(9):793-800 PMID: 15282802
- Wang X, et al. (2004) Role of DNA replication proteins in double-strand break-induced recombination in Saccharomyces cerevisiae. Mol Cell Biol 24(16):6891-9 PMID: 15282291
- Callahan JL, et al. (2003) Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility. Mol Cell Biol 23(21):7849-60 PMID: 14560028
- Lottersberger F, et al. (2003) Functions of Saccharomyces cerevisiae 14-3-3 proteins in response to DNA damage and to DNA replication stress. Genetics 165(4):1717-32 PMID: 14704161
- Muzi-Falconi M, et al. (2003) The DNA polymerase alpha-primase complex: multiple functions and interactions. ScientificWorldJournal 3:21-33 PMID: 12806117
- Pollok S, et al. (2003) Regulation of eukaryotic DNA replication at the initiation step. Biochem Soc Trans 31(Pt 1):266-9 PMID: 12546699
- Diaz RL, et al. (2002) Identification of residues in yeast Spo11p critical for meiotic DNA double-strand break formation. Mol Cell Biol 22(4):1106-15 PMID: 11809802
- Srivastava VK and Busbee DL (2002) Replicative enzymes and ageing: importance of DNA polymerase alpha function to the events of cellular ageing. Ageing Res Rev 1(3):443-63 PMID: 12067597
- Augustin MA, et al. (2001) Crystal structure of a DNA-dependent RNA polymerase (DNA primase). Nat Struct Biol 8(1):57-61 PMID: 11135672
- Bryant JA, et al. (2001) Origins and complexes: the initiation of DNA replication. J Exp Bot 52(355):193-202 PMID: 11283163
- Davis L, et al. (2001) The Saccharomyces cerevisiae MUM2 gene interacts with the DNA replication machinery and is required for meiotic levels of double strand breaks. Genetics 157(3):1179-89 PMID: 11238403
- Griffiths DJ, et al. (2001) Role of fission yeast primase catalytic subunit in the replication checkpoint. Mol Biol Cell 12(1):115-28 PMID: 11160827
- Ireland MJ, et al. (2000) The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast. Genetics 155(4):1657-65 PMID: 10924464
- Leipe DD, et al. (2000) The bacterial replicative helicase DnaB evolved from a RecA duplication. Genome Res 10(1):5-16 PMID: 10645945
- Masumoto H, et al. (2000) Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol Cell Biol 20(8):2809-17 PMID: 10733584
- Smith J, et al. (2000) Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance. Biochimie 82(1):71-8 PMID: 10717390
- Diede SJ and Gottschling DE (1999) Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. Cell 99(7):723-33 PMID: 10619426
- Holmes AM and Haber JE (1999) Double-strand break repair in yeast requires both leading and lagging strand DNA polymerases. Cell 96(3):415-24 PMID: 10025407
- Kamimura YI, et al. (1999) DNA helicase III of Saccharomyces cerevisiae, encoded by YER176w (HEL1), highly unwinds covalently closed, circular DNA in the presence of a DNA topoisomerase and yRF-A. J Biochem 125(2):236-44 PMID: 9990119
- Pajer P, et al. (1999) The "small" polydisperse cytoplasmic extrachromosomal DNA of chicken leukaemic myeloblasts and the avian myeloblastosis virus core-bound DNA seem to descend from origin regions of chromosomal DNA replication. Acta Virol 43(1):5-18 PMID: 10672338
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- Weinreich M and Stillman B (1999) Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. EMBO J 18(19):5334-46 PMID: 10508166
- Wittmeyer J, et al. (1999) Spt16 and Pob3 of Saccharomyces cerevisiae form an essential, abundant heterodimer that is nuclear, chromatin-associated, and copurifies with DNA polymerase alpha. Biochemistry 38(28):8961-71 PMID: 10413469
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