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CKM complex Overview

GO Annotations consist of four mandatory components: a gene product, a term from one of the three Gene Ontology (GO) controlled vocabularies (Molecular Function, Biological Process, and Cellular Component), a reference, and an evidence code.


Summary
Cyclin-dependent kinase complex which reversibly associates with the Mediator complex (CPX-3226). The mediator complex lacking the CKM complex has a stimulatory effect on basal transcription. In contrast, the mediator complex containing the sub-complex represses basal transcription. This effect is independent of kinase activity but binding of the complex to the Mediator may interfere with RNAPII recruitment and repress transcription re-initiation.
GO Slim Terms

The yeast GO Slim terms are higher level terms that best represent the major S. cerevisiae biological processes, functions, and cellular components. The GO Slim terms listed here are the broader parent terms for the specific terms to which this gene product is annotated, and thus represent the more general processes, functions, and components in which it is involved.

kinase activity, transferase activity, protein phosphorylation