Primary Literature
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- Gautam A and Beggs JD (2019) Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing. RNA Biol 16(2):185-195 PMID: 30672374
- Maudlin IE and Beggs JD (2019) Spt5 modulates cotranscriptional spliceosome assembly in <i>Saccharomyces cerevisiae</i>. RNA 25(10):1298-1310 PMID: 31289129
- Hálová M, et al. (2017) Nineteen complex-related factor Prp45 is required for the early stages of cotranscriptional spliceosome assembly. RNA 23(10):1512-1524 PMID: 28701519
- Schwer B, et al. (2017) Will the circle be unbroken: specific mutations in the yeast Sm protein ring expose a requirement for assembly factor Brr1, a homolog of Gemin2. RNA 23(3):420-430 PMID: 27974620
- Nguyen TH, et al. (2016) CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast. Curr Opin Struct Biol 36:48-57 PMID: 26803803
- Schwer B, et al. (2016) Structure-function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring. RNA 22(9):1320-8 PMID: 27417296
- Sorenson MR, et al. (2016) Histone H3K36 methylation regulates pre-mRNA splicing in Saccharomyces cerevisiae. RNA Biol 13(4):412-26 PMID: 26821844
- Yu SI, et al. (2016) Genetic Screening for Arabidopsis Mutants Defective in STA1 Regulation under Thermal Stress Implicates the Existence of Regulators of Its Specific Expression, and the Genetic Interactions in the Stress Signaling Pathways. Front Plant Sci 7:618 PMID: 27242824
- Absmeier E, et al. (2015) The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes Dev 29(24):2576-87 PMID: 26637280
- Gautam A, et al. (2015) Cwc21p promotes the second step conformation of the spliceosome and modulates 3' splice site selection. Nucleic Acids Res 43(6):3309-17 PMID: 25740649
- Rigo N, et al. (2015) Protein localisation by electron microscopy reveals the architecture of the yeast spliceosomal B complex. EMBO J 34(24):3059-73 PMID: 26582754
- Santos K, et al. (2015) Crystallization and biochemical characterization of the human spliceosomal Aar2-Prp8(RNaseH) complex. Acta Crystallogr F Struct Biol Commun 71(Pt 11):1421-8 PMID: 26527271
- Huang YH, et al. (2014) Sad1 counteracts Brr2-mediated dissociation of U4/U6.U5 in tri-snRNP homeostasis. Mol Cell Biol 34(2):210-20 PMID: 24190974
- Price AM, et al. (2014) An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8. RNA 20(1):46-60 PMID: 24231520
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- Livesay SB, et al. (2013) Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10. Eukaryot Cell 12(11):1472-89 PMID: 24014766
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- Nguyen TH, et al. (2013) Structural basis of Brr2-Prp8 interactions and implications for U5 snRNP biogenesis and the spliceosome active site. Structure 21(6):910-19 PMID: 23727230
- Weber G, et al. (2013) Structural basis for dual roles of Aar2p in U5 snRNP assembly. Genes Dev 27(5):525-40 PMID: 23442228
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- Horowitz DS (2012) The mechanism of the second step of pre-mRNA splicing. Wiley Interdiscip Rev RNA 3(3):331-50 PMID: 22012849
- Görnemann J, et al. (2011) Cotranscriptional spliceosome assembly and splicing are independent of the Prp40p WW domain. RNA 17(12):2119-29 PMID: 22020974
- Valadkhan S (2011) A snRNP's ordered path to maturity. Genes Dev 25(15):1563-7 PMID: 21828266
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- Grainger RJ, et al. (2009) Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome. RNA 15(12):2161-73 PMID: 19854871
- Kudlinzki D, et al. (2009) Crystallization and preliminary X-ray diffraction analysis of the C-terminal domain of the human spliceosomal DExD/H-box protein hPrp22. Acta Crystallogr Sect F Struct Biol Cryst Commun 65(Pt 9):956-8 PMID: 19724143
- Liu M, et al. (2009) GAMETOPHYTIC FACTOR 1, involved in pre-mRNA splicing, is essential for megagametogenesis and embryogenesis in Arabidopsis. J Integr Plant Biol 51(3):261-71 PMID: 19261069
- Maeder C, et al. (2009) ATP-dependent unwinding of U4/U6 snRNAs by the Brr2 helicase requires the C terminus of Prp8. Nat Struct Mol Biol 16(1):42-8 PMID: 19098916
- Zhao C, et al. (2009) Autosomal-dominant retinitis pigmentosa caused by a mutation in SNRNP200, a gene required for unwinding of U4/U6 snRNAs. Am J Hum Genet 85(5):617-27 PMID: 19878916
- Sapra AK, et al. (2008) The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis. Biochem J 416(3):365-74 PMID: 18691155
- Schwer B (2008) A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release. Mol Cell 30(6):743-54 PMID: 18570877
- Boon KL, et al. (2007) prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast. Nat Struct Mol Biol 14(11):1077-83 PMID: 17934474
- Tsai RT, et al. (2007) Dynamic interactions of Ntr1-Ntr2 with Prp43 and with U5 govern the recruitment of Prp43 to mediate spliceosome disassembly. Mol Cell Biol 27(23):8027-37 PMID: 17893323
- Bellare P, et al. (2006) Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA 12(2):292-302 PMID: 16428608
- Boon KL, et al. (2006) Prp8p dissection reveals domain structure and protein interaction sites. RNA 12(2):198-205 PMID: 16373487
- Boon KL, et al. (2006) Yeast ntr1/spp382 mediates prp43 function in postspliceosomes. Mol Cell Biol 26(16):6016-23 PMID: 16880513
- Brenner TJ and Guthrie C (2006) Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain. RNA 12(5):862-71 PMID: 16540695
- Brenner TJ and Guthrie C (2005) Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation. Genetics 170(3):1063-80 PMID: 15911574
- Görnemann J, et al. (2005) Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex. Mol Cell 19(1):53-63 PMID: 15989964
- Grainger RJ and Beggs JD (2005) Prp8 protein: at the heart of the spliceosome. RNA 11(5):533-57 PMID: 15840809
- Verdone L, et al. (2004) Lsm proteins promote regeneration of pre-mRNA splicing activity. Curr Biol 14(16):1487-91 PMID: 15324666
- Bartels C, et al. (2003) Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing. J Biol Chem 278(30):28324-34 PMID: 12736260
- Bartels C, et al. (2002) The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome. EMBO Rep 3(9):875-80 PMID: 12189173
- Jurica MS, et al. (2002) Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. RNA 8(4):426-39 PMID: 11991638
- Makarova OV, et al. (2002) Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing. EMBO J 21(5):1148-57 PMID: 11867543
- Mougin A, et al. (2002) Direct probing of RNA structure and RNA-protein interactions in purified HeLa cell's and yeast spliceosomal U4/U6.U5 tri-snRNP particles. J Mol Biol 317(5):631-49 PMID: 11955014
- Ohi MD, et al. (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24 PMID: 11884590
- Stevens SW, et al. (2002) Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol Cell 9(1):31-44 PMID: 11804584
- Gottschalk A, et al. (2001) The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p. RNA 7(11):1554-65 PMID: 11720285
- Gottschalk A, et al. (2001) A novel yeast U2 snRNP protein, Snu17p, is required for the first catalytic step of splicing and for progression of spliceosome assembly. Mol Cell Biol 21(9):3037-46 PMID: 11287609
- Stevens SW, et al. (2001) Biochemical and genetic analyses of the U5, U6, and U4/U6 x U5 small nuclear ribonucleoproteins from Saccharomyces cerevisiae. RNA 7(11):1543-53 PMID: 11720284
- van Nues RW and Beggs JD (2001) Functional contacts with a range of splicing proteins suggest a central role for Brr2p in the dynamic control of the order of events in spliceosomes of Saccharomyces cerevisiae. Genetics 157(4):1451-67 PMID: 11290703
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- Kuhn AN and Brow DA (2000) Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation. Genetics 155(4):1667-82 PMID: 10924465
- Makarov EM, et al. (2000) The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. J Mol Biol 298(4):567-75 PMID: 10788320
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