W303-derivative K6001 is a key model organism for research into aging, and shares >85% of its genome with S288C, differing at >8000 nucleotide positions, causing changes to the sequences of 799 proteins. These differences are distributed non-randomly throughout the genome, with chromosome XVI being almost identical between the two strains, and chromosome XI the most divergent. Some of the non-S288C regions in W303 are also present in Sigma1278b.
Genome sequence information for a particular strain, including GenBank accession IDs and assembly statistics. The table below lists all contigs included in the genome, listed by GenBank accession, with information regarding where that contig maps to the S288C Reference Genome. Note that only the single best BLAST hit for each contig is shown, based on highest bit score from a pairwise BLAST of the genome against S288C using NCBI’s Genome BLAST tool.
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| Contig ID | Best BLAST Hit to S288C Reference Genome | % Identity | Alignment Length |
|---|---|---|---|
| JRIU01000001.1 | chrI:11725..2674 | 99.99 | 9053 |
| JRIU01000002.1 | chrXVI:174133..136404 | 99.98 | 37730 |
| JRIU01000003.1 | chrVII:364399..323358 | 99.53 | 41072 |
| JRIU01000004.1 | chrXII:95858..64793 | 100 | 31066 |
| JRIU01000006.1 | chrXI:579035..618258 | 99.3 | 39244 |
| JRIU01000007.1 | chrXV:900407..780412 | 99.98 | 119996 |
| JRIU01000008.1 | chrXVI:810711..823613 | 100 | 12903 |
| JRIU01000009.1 | chrIII:124169..90945 | 99.99 | 33227 |
| JRIU01000010.1 | chrXIV:599689..632085 | 99.95 | 32399 |
| JRIU01000011.1 | chrIII:200890..199401 | 99.93 | 1490 |