Beyond their well-known roles in chromosome end protection, telomeres play critical roles in ensuring the fidelity of meiosis, the specialized cell division underlying sexual reproduction. Central to this process is the conserved telomere bouquet, a polarized nuclear arrangement in which telomeres cluster beneath the centrosome. The telomere bouquet orchestrates movements of meiotic chromosomes that facilitate pairing and recombination between homologous chromosomes, the defining events of meiosis. Here, we review both this canonical function and newly discovered meiotic telomere functions. We focus on three species-fission yeast, budding yeast, and mouse-that highlight both general principles and novel insights likely to be broadly applicable across eukaryotes. We propose that these diverse telomere functions provided early eukaryotes with a powerful adaptive advantage, contributing to the evolutionary success of linear chromosomes.
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| Evidence ID | Analyze ID | Gene/Complex | Systematic Name/Complex Accession | Qualifier | Gene Ontology Term ID | Gene Ontology Term | Aspect | Annotation Extension | Evidence | Method | Source | Assigned On | Reference |
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| Evidence ID | Analyze ID | Gene | Gene Systematic Name | Phenotype | Experiment Type | Experiment Type Category | Mutant Information | Strain Background | Chemical | Details | Reference |
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| Evidence ID | Analyze ID | Gene | Gene Systematic Name | Disease Ontology Term | Disease Ontology Term ID | Qualifier | Evidence | Method | Source | Assigned On | Reference |
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| Evidence ID | Analyze ID | Regulator | Regulator Systematic Name | Target | Target Systematic Name | Direction | Regulation of | Happens During | Regulator Type | Direction | Regulation Of | Happens During | Method | Evidence | Strain Background | Reference |
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| Site | Modification | Modifier | Source | Reference |
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| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Assay | Annotation | Action | Modification | Source | Reference | Note |
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| Complement ID | Locus ID | Gene | Species | Gene ID | Strain background | Direction | Details | Source | Reference |
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| Evidence ID | Analyze ID | Dataset | Description | Keywords | Number of Conditions | Reference |
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