Reference: Washington MT and Gildenberg MS (2020) Structure of DNA polymerase ζ: capturing the getaway driver. Nat Struct Mol Biol 27(10):1-2

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Abstract


During translesion synthesis, eukaryotic DNA polymerase ζ (zeta) carries out extension from a wide range of DNA lesions. In this issue, Malik et al. (2020) (1) present the cryo-EM structure of polymerase ζ and show how it catalyzes the extension step of translesion synthesis.

Reference Type
Journal Article
Authors
Washington MT, Gildenberg MS