Reference: Smith AB and Chekan JR (2023) Engineering yeast for industrial-level production of the antimalarial drug artemisinin. Trends Biotechnol 41(3):267-269

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Abstract


Artemisinin-based combination therapies are the gold standard treatment for uncomplicated malaria. A seminal study by Paddon et al. detailed an efficient approach for producing artemisinic acid from engineered yeast and its conversion to artemisinin, and demonstrated how to use metabolic engineering and synthetic biology for the production of bioactive compounds.

Reference Type
Journal Article
Authors
Smith AB, Chekan JR