Reference: Zhong Y, et al. (2020) Repairing Creep-Resistant and Kinetically Inert Hydrogels via Yeast Activity-Regulated Energy Dissipation. ACS Appl Bio Mater 3(7):4507-4513

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Abstract


Energy dissipation, a ubiquitous process in biological systems, has been intensively studied and widely used to guide the transient assembly of natural or synthetic molecules, but very few examples of material transient healability controlled by this important process have been reported. Herein, we realize the healing of creep-resistant and kinetically inert polymer hydrogels that is driven by the respiration of baker's yeast (Saccharomyces cerevisiae) and spontaneous energy dissipation. The entire healing process can be simply controlled by a single variable: sucrose concentration. Due to the high activity and stability of yeast in the hydrogels, multiple local healing events become possible and healing of damaged hydrogels is also efficient after a long waiting time. All these results indicate that our yeast-containing polymer hydrogels are kinetically stable materials, which can be readily healable on demand.

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Journal Article
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Zhong Y, Chen T, Wang X
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