Reference: Mohd Ali N, et al. (2016) Web application for genetic modification flux with database to estimate metabolic fluxes of genetic mutants. J Biosci Bioeng 122(1):111-6

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Abstract


Computational analysis of metabolic fluxes is essential in understanding the structure and function of a metabolic network and in rationally designing genetically modified mutants for an engineering purpose. We had presented the genetic modification flux (GMF) that predicts the flux distribution of a broad range of genetically modified mutants. To enhance the feasibility and usability of GMF, we have developed a web application with a metabolic network database to predict a flux distribution of genetically modified mutants. One hundred and twelve data sets of Escherichia coli, Corynebacterium glutamicum, Saccharomyces cerevisiae, and Chinese hamster ovary were registered as standard models.

Reference Type
Journal Article
Authors
Mohd Ali N, Tsuboi R, Matsumoto Y, Koishi D, Inoue K, Maeda K, Kurata H
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