Reference: Hara KY, et al. (2012) An energy-saving glutathione production method from low-temperature cooked rice using amylase-expressing Saccharomyces cerevisiae. Biotechnol J 7(5):686-9

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Abstract


Glutathione is a valuable tripeptide that is widely used in the pharmaceutical, food, and cosmetic industries. Glutathione is industrially produced by fermentation using Saccharomyces cerevisiae. Before the glutathione fermentation process with S. cerevisiae, a glucose extraction process from starchy materials is required. This glucose extraction is usually carried out by converting starchy materials to starch using high-temperature cooking and subsequent hydrolysis by amylases to convert starch to glucose. In this study, to develop an energy-saving glutathione production process by reducing energy consumption during the cooking step, we efficiently produced glutathione from low-temperature cooked rice using amylase-expressing S. cerevisiae. The combination of the amylase-expressing yeast with low-temperature cooking is potentially applicable to a variety of energy-saving bio-production methods of chemicals from starchy bio-resources.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
Hara KY, Kim S, Kiriyama K, Yoshida H, Arai S, Ishii J, Ogino C, Fukuda H, Kondo A
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