Reference: Yutani M, et al. (2011)
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Abstract
Sporulation of the yeast Saccharomyces cerevisiae is negatively regulated by cyclic AMP (cAMP). This microbial cell differentiation process was applied for the screening of a substance that can elevate the intracellular cAMP level. Among nucleoside 5'-alkylphosphates, uridine 5'-eicosylphosphate (UMPC20) selectively and predominantly inhibited ascospore formation of the yeast cells. We suppose the inhibitory effect of UMPC20 could indeed reflect the elevation of the cellular cAMP level.
- Reference Type
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Journal Article
- Authors
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Yutani M,
Ogita A,
Fujita K,
Usuki Y,
Tanaka T
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