Reference: Dever TE (2002) Gene-specific regulation by general translation factors. Cell 108(4):545-56

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Abstract


Protein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, processing, or export. Recent studies have enhanced our understanding of the translation initiation process and helped elucidate how modifications of the general translational machinery regulate gene-specific protein production.

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Journal Article | Research Support, U.S. Gov't, P.H.S. | Review
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Dever TE
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