Reference: Núñez L, et al. (2004) The KlSRB10 gene from Kluyveromyces lactis. Yeast 21(6):511-8

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Abstract


We report the cloning and sequencing of a gene from Kluyveromyces lactis with high homology to the SRB10 gene (alias UME5, SSN3, GIG2, NUT7, RYE5) from Saccharomyces cerevisiae and other organisms. The KlSRB10 gene is located in a similar configuration to that found in S. cerevisiae, flanked by NOT4 and a gene with high similarity to YPL041c. The translated protein contains 593 amino acids and the characteristic domains of kinases from the CMGC subgroup. The functional relationship to yeast SRB10 is demonstrated by complementation of mutant phenotypes in a haploid S. cerevisiae strain containing a null allele.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't
Authors
Núñez L, Fernández-Otero C, Rodríguez-Belmonte E, Cerdán ME
Additional Lit For
MOT2 | MRX11 | SSN3