Reference: Matunis MJ (2002) On the road to repair: PCNA encounters SUMO and ubiquitin modifications. Mol Cell 10(3):441-2

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Abstract


The molecular events and targets regulated by the RAD6 pathway, which mediates postreplication DNA repair, have remained elusive. Now, ubiquitin and SUMO modification of proliferating cell nuclear antigen (PCNA) is shown to be induced by DNA damage and linked to components of the RAD6 pathway.

Reference Type
Journal Article | Review
Authors
Matunis MJ
Primary Lit For
PCNA homotrimer
Review For
POL30 | RAD6