Reference: Geiduschek EP and Kassavetis GA (1995) Comparing transcriptional initiation by RNA polymerases I and III. Curr Opin Cell Biol 7(3):344-51

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Abstract


We comment on the current understanding of transcriptional initiation by RNA polymerases I and III, and look for common modes of operation of these enzymes, emphasizing selected recent developments. These include definitive experiments on the constitution of the human RNA polymerase I transcription factor SL1/TIF-IB, the development of a genetic system for analyzing the function of RNA polymerase I in yeast, the elucidation of the structure of the human snRNA gene transcription factor SNAPc, and initial stages of mapping the protein-protein interactions involved in the assembly of transcriptional initiation complexes.

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Comparative Study | Journal Article | Review
Authors
Geiduschek EP, Kassavetis GA
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