Reference: Bilinski T, et al. (1981) Characterization of two mutant strains of Saccharomyces cerevisiae deficient in coproporphyrinogen III oxidase activity. J Gen Microbiol 122(1):79-87

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Abstract


Two new haem-deficient mutants of Saccharomyces cerevisiae were isolated on the basis of their catalase deficiency. Mutant H11 accumulated and excreted coproporphyrin III and was completely deficient in haem; the cell-free extract had no coproporphyrinogen oxidase activity. Mutant H12 accumulated uroporphyrin to coproporphyrin III and excreted coproporphyrin III, and contained a small amount of haem; the cell-free extract had a residual coproporphyrinogen oxidase activity. The two mutations were allelic and the mutant phenotypes were under the control of a single, recessive nuclear gene.

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Journal Article | Research Support, Non-U.S. Gov't
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Bilinski T, Litwinska J, Lukaskiewicz J, Rytka J, Simon M, Labbe-Bois R
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