Reference: Koch C and Nasmyth K (1994) Cell cycle regulated transcription in yeast. Curr Opin Cell Biol 6(3):451-9

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Abstract


At least four different classes of cell cycle regulated gene exist in yeast: G1 cyclins and DNA synthesis genes are expressed in late G1; histone genes in S phase; genes for transcription factors, cell cycle regulators and replication initiation proteins in G2; and genes needed for cell separation as cells enter G1. Early and late G1-specific transcription is mediated by the Swi5/Ace2 and Swi4/Swi6 classes of factor, respectively. Changes in cyclin/Cdc28 kinases may be involved in all classes of regulation. Transcriptional control of cyclin genes has an important role in regulating cell cycle progression.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't | Review
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Koch C, Nasmyth K
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