The combined action of hyperthermia and ionizing radiation on the arrival of isogenic haploid and diploid yeast cells of wild type and rad51 mutant was studied. The experiments demonstrated the essential enhancement of radiosensitivity of diploid wild type cells is hyperthermic conditions. For haploid wild type cells and rad51 mutant cells the enhancement was smaller and negligible respectively. The action of both factors on rad51 homozygous diploid cells was additive. It is established that diploid cells were less thermosensitive than haploid ones. Rad51 mutation does not change these properties. It was concluded that the enhancement of radiosensitivity of cells under hyperthermic conditions depends on cell genotype and may be caused by the reduced capacity of cells to recover the radiation damages inflicted by the both modalities.
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| Evidence ID | Analyze ID | Gene/Complex | Systematic Name/Complex Accession | Qualifier | Gene Ontology Term ID | Gene Ontology Term | Aspect | Annotation Extension | Evidence | Method | Source | Assigned On | Reference |
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| Evidence ID | Analyze ID | Gene | Gene Systematic Name | Phenotype | Experiment Type | Experiment Type Category | Mutant Information | Strain Background | Chemical | Details | Reference |
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| Evidence ID | Analyze ID | Gene | Gene Systematic Name | Disease Ontology Term | Disease Ontology Term ID | Qualifier | Evidence | Method | Source | Assigned On | Reference |
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| Evidence ID | Analyze ID | Regulator | Regulator Systematic Name | Target | Target Systematic Name | Direction | Regulation of | Happens During | Regulator Type | Direction | Regulation Of | Happens During | Method | Evidence | Strain Background | Reference |
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| Site | Modification | Modifier | Source | Reference |
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| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Allele | Assay | Annotation | Action | Phenotype | SGA score | P-value | Source | Reference | Note |
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| Evidence ID | Analyze ID | Interactor | Interactor Systematic Name | Interactor | Interactor Systematic Name | Assay | Annotation | Action | Modification | Source | Reference | Note |
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| Complement ID | Locus ID | Gene | Species | Gene ID | Strain background | Direction | Details | Source | Reference |
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| Evidence ID | Analyze ID | Dataset | Description | Keywords | Number of Conditions | Reference |
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