Reference: Suslova NG, et al. (1975) [Effect of uvs1, uvs2 and xrs mutations on the radiosensitivity of and frequency of induced mitotic recombination in diploid yeast cells]. Genetika 11(11):58-66

Reference Help

Abstract


Effect of radiosensitivity mutations uvs1, uvs2 and xrs in homozygous state in yeast Saccharomyces cerevisiae on UV and X-ray sensitivity and on the induced mitotic recombination is studied. Diploids uvs2 uvs2 xrs xrs are much more UV-sensible than diploids UVS2 UVS2 xrs xrs or UVS2 uvs2 xrs xrs. Diploids uvs1 uvs1 uvs2 uvs2 and uvs1 uvs1 UVS2 UVS2 have the same radiosensitivity. These data show that mutations uvs1, uvs2 and xrs block different ways of the elimination of UV-induced damages. The diploid uvs2 uvs2 xrs3 xrs3 is much more X-ray sensible, than the diploid UVS2 UVS2 xrs3 xrs3. It shows that mutations uvs2 and xrs3 block different ways of the elimination of X-ray induced damages. All double mutant diploids are characterized by a higher frequency of UV-induced mitotic recombination, than the diploid UVS UVS XRS XRS and the UV-sensitive diploid uvs2 uvs2 XRS XRS. The diploid uvs2 uvs2 xrs5 xrs5 is characterized by an extraordinary high frequency of X-RAY INDUCED MITOTIC RECOMBINATION.

Reference Type
Journal Article
Authors
Suslova NG, Fedorova IV, Zhelezniakova NIu
Primary Lit For
Additional Lit For
Review For

Gene Ontology Annotations


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Phenotype Annotations


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference

Disease Annotations


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Gene Disease Ontology Term Qualifier Evidence Method Source Assigned On Reference

Regulation Annotations


Increase the total number of rows displayed on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; to filter the table by a specific experiment type, type a keyword into the Filter box (for example, “microarray”); download this table as a .txt file using the Download button or click Analyze to further view and analyze the list of target genes using GO Term Finder, GO Slim Mapper, or SPELL.

Regulator Target Direction Regulation Of Happens During Method Evidence

Post-translational Modifications


Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Site Modification Modifier Reference

Interaction Annotations


Genetic Interactions

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.

Interactor Interactor Allele Assay Annotation Action Phenotype SGA score P-value Source Reference

Physical Interactions

Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details about experiment type and any other genes involved in the interaction.

Interactor Interactor Assay Annotation Action Modification Source Reference

Functional Complementation Annotations


Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

Gene Species Gene ID Strain background Direction Details Source Reference