Reference: Bollon AP (1975) Regulation of the ilv 1 multifunctional gene in Saccharomyces cerevisiae. Mol Gen Genet 142(1):1-12

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Abstract


The ilv 1 gene in S. cerevisiae codes for a regulatory protein involved in depression of the ilv 2 and ilv 3 genes as well as a biosynthetic enzyme, threonine deaminase. 2. The ilv 1 gene does not autogenously regulate its catalytic product threonine deaninase. 3. Regulation of the ilv 2 and ilv 3 gene products involve different aporepressors than regulation of the ilv 1 gene product. 4. The ilv I multifunctional gene in S. cerevisiae may be a duplication and fusion of a bacterial like ilv 1 gene where ilv 1 catalytic and regulatory function have been differentially conserved.

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Journal Article | Research Support, U.S. Gov't, Non-P.H.S.
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Bollon AP
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