Reference: Koettnitz K, et al. (1995) Identification of a new member of the human eIF-5A gene family. Gene 159(2):283-4

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Abstract


Using an oligodeoxynucleotide generated by rapid PCR amplification of 5'-cDNA ends (5'-RACE) as a detection probe, we have isolated a new genomic clone encoding the human eukaryotic initiation factor 5A (eIF-5A). Sequence analysis revealed that the eIF-5A coding region is identical to the corresponding cDNA but interrupted by three introns. In a plasmid shuffle experiment we show functional replacement of the essential homologous gene in Saccharomyces cerevisiae by this human eIF-5A.

Reference Type
Journal Article
Authors
Koettnitz K, Wöhl T, Kappel B, Lottspeich F, Hauber J, Bevec D
Additional Lit For
ANB1 | HYP2

Functional Complementation Annotations 1 entry for 1 complement


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GeneSpeciesGene IDStrain backgroundDirectionDetailsSource
HYP2Homo sapiensHGNC:3300S288Cother complements yeastHuman EIF5A complements the inviability of the yeast hyp2 null mutant.SGD
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