Reference: Silver JM and Eaton NR (1969) Functional blocks of the ad-1 and ad-2 mutants of Saccharomyces cerevisiae. Biochem Biophys Res Commun 34(3):301-5

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Abstract


Spectrophotometric analyses of Bratton-Marshall chromophores in deproteinized extracts of ad1 and ad2 mutants of S. cerevisiae indicated that ad2 was blocked at the conversion of AIR to CAIR and ad1 at the conversion of CAIR to SAICAR. The demonstration, that the introduction of an ad2 marker into an ad1 strain results in the elimination of a C14-glycine-labelled, Pauly-positive compound characteristic of the ad1 strain, further supports the conclusion that the block of ad2 precedes that of ad1.

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Journal Article
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Silver JM, Eaton NR
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