Reference: Burkl G, et al. (1972) Mapping of a complex gene locus coding for part of the Saccharomyces cerevisiae fatty acid synthetase multienzyme complex. Mol Gen Genet 119(4):315-22

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Abstract


Using two different experimental approaches--UV induced mitotic recombination and meiotic segregation--a fatty acid synthetase gene locus has been mapped on chromosome Fragment V of the Saccharomyces cerevisiae genetic map. This locus has been tentatively designated as faslAB since it is a complex locus coding for at least two different fatty acid synthetase component enzymes, namely the beta-hydroxyacid dehydratase and the enoyl reductase. According to the meiotic segregation patterns obtained, faslAB is 41.6 centimorgans from ural and 35.7 centimorgans from trp3. Furthermore, the same criteria of mitotic sectoring and meiotic segregation indicate that the second known fatty acid synthetase gene cluster in yeast is genetically unlinked to faslAB or to any other of the known genetic loci on Fragment V.

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Journal Article
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Burkl G, Castorph H, Schweizer E
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