Reference: Rymo L, et al. (1972) Subunit structure and binding properties of three amino acid transfer ribonucleic acid ligases. J Biol Chem 247(12):3888-97

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Abstract


The subunit structure and binding properties of valine: tRNA ligase from yeast and the lysine: tRNA ligases from Escherichia coli and yeast have been investigated. Both the lysine:tRNA ligase from E. coli and that from yeast contain two subunits of identical molecular weight per molecule of active enzyme. Binding studies show that both enzymes have two lysine sites and two ATP sites. In contrast to this the valine: tRNA ligase contains only one polypeptide chain and has one site each for valine and ATP per enzyme molecule.

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Journal Article
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Rymo L, Lundvik L, Lagerkvist U
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