Reference: Gardner JH and Byers LD (1977) Enzymic reactions of phosphate analogs. J Biol Chem 252(17):5925-7

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Abstract


A variety of phosphonates (XPO32-; X = H-, CH3-, CL3C-, CH3CH2-, and phenyl-) as well as methylarsonate have been shown to be suitable phosphate analogs for the reactions catalyzed by yeast glyceraldehyde-3-phosphate dehydrogenase and calf spleen purine nucleoside phosphorylase. The reactivity of the phosphate analogs with these two enzymes is independent of the pKa of the analog.

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Journal Article
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Gardner JH, Byers LD
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