Reference: Karpov DS, et al. (2009)
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Abstract
The ubuquitin-proteasome system is involved in degradation of many intracellular proteins and is necessary for proper functioning of the cell under normal conditions and its survival under stress conditions. In this review the general principles of structure and functioning of the ubiquitin-proteasome proteolytic system is considered. The main attention was paid for regulation of proteasomal genes expression, and specifically for discovery and analysis of Rpn4p transcription factor, an activator for proteasomal genes in Saccharomyces cerevisiae. The data about regulation of proteasomal genes expression in higher eukaryotes is also discussed.
- Reference Type
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Journal Article |
Review
- Authors
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Karpov DS,
Preobrazhenskaia OV,
Karpov VL
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- RPN4
Gene Ontology Annotations
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Evidence ID |
Analyze ID |
Gene/Complex |
Systematic Name/Complex Accession |
Qualifier |
Gene Ontology Term ID |
Gene Ontology Term |
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Annotation Extension |
Evidence |
Method |
Source |
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Reference |
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Gene |
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Reference |
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Analyze ID |
Gene |
Gene Systematic Name |
Disease Ontology Term |
Disease Ontology Term ID |
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Reference |
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Evidence ID |
Analyze ID |
Regulator |
Regulator Systematic Name |
Target |
Target Systematic Name |
Direction |
Regulation of |
Happens During |
Regulator Type |
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Regulation Of |
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Evidence |
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Reference |
Post-translational Modifications
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Interactor |
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Interactor |
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Interactor |
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Complement ID |
Locus ID |
Gene |
Species |
Gene ID |
Strain background |
Direction |
Details |
Source |
Reference |