Reference: Kulakovskaia EV, et al. (2008) [Effects of cellobiose lipid B on Saccharomyces cerevisiae cells: K+ leakage and inhibition of polyphosphate accumulation]. Mikrobiologiia 77(3):331-5

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Abstract


Cellobiose lipid B, a natural fungicide produced by the yeast Pseudozyma fusiformata, induces the leakage of K+ and ATP from cells of Saccharomyces cerevisiae. The presence of glucose decreases the effective concentration of cellobiose lipid B. The concentration of cellobiose lipid B was selected that results in a high rate of K+ leakage and a five- to sevenfold decrease in the intracellular ATP content, while the accumulation of acid-soluble polyphosphates decreased only by half. These results indicate the possibility of synthesis of these polymers independently of the ATP level and of the ion gradient on the plasma membrane.

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Journal Article | Research Support, Non-U.S. Gov't
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Kulakovskaia EV, Ivanov AIu, Kulakovskaia TV, Vagabov VM, Kulaev IS
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