Reference: Henderson ER and Larson DD (1991) Telomeres--what's new at the end? Curr Opin Genet Dev 1(4):538-43

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Abstract


Telomeres are specialized chromatin domains located at the ends of chromosomes. They are involved in chromosome replication, stability and localization in the nucleus. In addition to these functions, recent work suggests that telomeres are involved in such superficially diverse cellular phenomena as ageing, cancer, nuclear architecture and nuclear/cellular division.

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Journal Article | Research Support, Non-U.S. Gov't | Research Support, U.S. Gov't, Non-P.H.S. | Research Support, U.S. Gov't, P.H.S. | Review
Authors
Henderson ER, Larson DD
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