Reference: Adkins NL, et al. (2004) To the 30-nm chromatin fiber and beyond. Biochim Biophys Acta 1677(1-3):12-23

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Abstract


Chromatin fibers are intrinsically dynamic macromolecular complexes whose biological functions are intimately linked with their structure and interactions with chromatin-associated proteins (CAPs). Three-dimensional architectural transitions between or within the two co-existing chromatin types referred to as euchromatin and heterochromatin have been associated with activation or repression of nuclear functions. The presence of specific subsets of chromosomal proteins co-existing with the different chromatin conformations suggests a functional significance for their co-localization. The major points of emphasis of this review will assess the structure, function and recently documented exchanges amongst various members of the CAP family.

Reference Type
Journal Article | Review
Authors
Adkins NL, Watts M, Georgel PT
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