Reference: SPOERL E and CARLETON R (1954) Studies on cell division; nitrogen compound changes in yeast accompanying an inhibition of cell division. J Biol Chem 210(2):521-9

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Abstract


Cell division in yeast has been shown in previous reports to be selectively inhibited by radiation (1) and by several chemicals. A specific effect had been sought so that biochemical changes in the cell might be correlated with an inhibition of division. Though cellular changes occurring at division are the basic information from which an understanding of the mechanisms involved in cell division must be built, only a few data on such changes are available in the literature (see Hughes (2) and Heilbrunn (3)). This paper reports changes in amounts of major nitrogen fractions and free amino acids of division-inhibited yeast cells. Three division-inhibiting agents have been compared and found to produce quite similar patterns of change.

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SPOERL E, CARLETON R
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