Reference: Bader GD, et al. (2003) Functional genomics and proteomics: charting a multidimensional map of the yeast cell. Trends Cell Biol 13(7):344-56

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Abstract


The challenge of large-scale functional genomics projects is to build a comprehensive map of the cell including genome sequence and gene expression data, information on protein localization, structure, function and expression, post-translational modifications, molecular and genetic interactions and phenotypic descriptions. Some of this broad set of functional genomics data has been already assembled for the budding yeast. Even though molecular cartography of the yeast cell is still far from comprehensive, functional genomics has begun to forge connections between disparate cellular events and to foster numerous hypotheses. Here we review several different genomics and proteomics technologies and describe bioinformatics methods for exploring these data to make new discoveries.

Reference Type
Journal Article | Review
Authors
Bader GD, Heilbut A, Andrews B, Tyers M, Hughes T, Boone C
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Gene Ontology Annotations


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Gene Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

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Gene Phenotype Experiment Type Mutant Information Strain Background Chemical Details Reference

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Gene Disease Ontology Term Qualifier Evidence Method Source Assigned On Reference

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Site Modification Modifier Reference

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Interactor Interactor Type Assay Annotation Action Modification Phenotype Source Reference