Reference: Durocher D and Jackson SP (2002) The FHA domain. FEBS Lett 513(1):58-66

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Abstract


The forkhead-associated (FHA) domain is a small protein module recently shown to recognize phosphothreonine epitopes on proteins. It is present in a diverse range of proteins in eukaryotic cells, such as kinases, phosphatases, kinesins, transcription factors, RNA-binding proteins, and metabolic enzymes. It is also found in a number of bacterial proteins. This suggests that FHA domain-mediated phospho-dependent assembly of protein complexes is an ancient and widespread regulatory mechanism.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't | Review
Authors
Durocher D, Jackson SP
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