Reference: Paull TT (2001) New glimpses of an old machine. Cell 107(5):563-5

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Abstract


Two recent studies illustrate the ability of the Mre11/Rad50 DNA repair complex to bind and connect DNA ends. Specific stimulation of DNA ligase IV-mediated end-joining by Mre11 complexes from S. cerevisiae suggests the possibility of a direct role in nonhomologous end-joining in eukaryotic cells.

Reference Type
Journal Article | Review
Authors
Paull TT
Primary Lit For
DNA ligase IV complex
Review For
MRE11 | RAD50