Reference: MacNeill SA (2001) DNA replication: partners in the Okazaki two-step. Curr Biol 11(20):R842-4

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Abstract


The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.

Reference Type
Journal Article | Research Support, Non-U.S. Gov't | Review
Authors
MacNeill SA
Review For
DNA2