Reference: Minvielle-Sebastia L and Keller W (1999) mRNA polyadenylation and its coupling to other RNA processing reactions and to transcription. Curr Opin Cell Biol 11(3):352-7

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Abstract


Eukaryotic mRNA precursors are processed at their 3' ends by a coupled cleavage/polyadenylation reaction. In recent years, most of the factors involved in 3'-end processing have been identified and evidence has been presented for the coupling of mRNA 3'-end formation to capping, splicing and transcription. These links are important for the quality control of the mRNA during synthesis.

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Journal Article | Research Support, Non-U.S. Gov't | Review
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Minvielle-Sebastia L, Keller W
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