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| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| CDC16 | cell cycle progression in G2 phase: arrested | classical genetics | conditional Allele: cdc16-264 | S288C | Temperature: elevated temperature, 36 °C Treatment: alpha-factor block release Details: ~90% of cells exhibit a first cycle arrest in a G2-like state as large-budded cells with a short mitotic spindle and a single nucleus positioned at the bud neck; accumulates 2-4 times more nuclear DNA than wild-type (4C to 8C) cells due to overreplication | Heichman KA and Roberts JM (1996) PMID:8620535 | |
| CDC16 | cell cycle progression in G2 phase: arrested | classical genetics | conditional Allele: cdc16-299 | S288C | Temperature: elevated temperature, 36 °C Treatment: alpha-factor block release Details: ~90% of cells exhibit a first cycle arrest in a G2-like state as large-budded cells with a short mitotic spindle and a single nucleus positioned at the bud neck; accumulates 2-4 times more nuclear DNA than wild-type (4C to 8C) cells due to overreplication | Heichman KA and Roberts JM (1996) PMID:8620535 | |
| CDC16 | cell cycle progression in G2 phase: arrested | classical genetics | conditional Allele: cdc16-1 | S288C | Temperature: elevated temperature, 36 °C Treatment: alpha-factor block release Details: ~90% of cells exhibit a first cycle arrest in a G2-like state as large-budded cells with a short mitotic spindle and a single nucleus positioned at the bud neck; accumulates 2-4 times more nuclear DNA than wild-type (4C to 8C) cells due to overreplication | Heichman KA and Roberts JM (1996) PMID:8620535 | |
| CDC27 | cell cycle progression in G2 phase: arrested | classical genetics | conditional Allele: cdc27-22 | S288C | Temperature: elevated temperature, 36 °C Treatment: alpha-factor block release Details: ~80% of cells exhibit a first cycle arrest in a G2-like state as large-budded cells; ~59% of cells arrest with a short mitotic spindle and a single nucleus while 41% contain two well separated nuclei and an elongated or post-mitotic spindle; accumulates 2-4 times more nuclear DNA than wild-type (4C to 8C) cells due to overreplication | Heichman KA and Roberts JM (1996) PMID:8620535 | |
| CDC27 | cell cycle progression in G2 phase: arrested | classical genetics | conditional Allele: cdc27-283 | S288C | Temperature: elevated temperature, 36 °C Treatment: alpha-factor block release Details: ~80% of cells exhibit a first cycle arrest in a G2-like state as large-budded cells; ~75% of cells arrest with a short mitotic spindle and a single nucleus while 25% contain two well separated nuclei and an elongated or post-mitotic spindle; accumulates 2-4 times more nuclear DNA than wild-type (4C to 8C) cells due to overreplication | Heichman KA and Roberts JM (1996) PMID:8620535 | |
| CDC27 | cell cycle progression in G2 phase: arrested | classical genetics | conditional Allele: cdc27-1 | S288C | Temperature: elevated temperature, 36 °C Treatment: alpha-factor block release Details: ~80% of cells exhibit a first cycle arrest in a G2-like state as large-budded cells; 97% arrest with a short mitotic spindle and a single undivided nucleus; accumulates 2-4 times more nuclear DNA than wild-type (4C to 8C) cells due to overreplication treatment: alpha-factor block release | Heichman KA and Roberts JM (1996) PMID:8620535 | |
| MPS2 | cell cycle progression in G2 phase: arrested | homozygous diploid | conditional Allele: mps2-1 | Other | Temperature: elevated temperature, 36 °C Details: arrest as large-budded cells with a G2 DNA content | Winey M, et al. (1991) PMID:1869587 | |
| RPN12 | cell cycle progression in G2 phase: arrested | classical genetics | conditional Allele: rpn12-(nin1-1) | Other | Temperature: elevated temperature, 37 °C | Nisogi H, et al. (1992) PMID:1563492 | |
| SFI1 | cell cycle progression in G2 phase: arrested | classical genetics | repressible | Other | Details: large-budded cells with a single nucleus at the neck; 90% unable to assemble mitotic spindles and remainder had a short mitotic spindle | Ma P, et al. (1999) PMID:10455233 | |
| SWE1 | cell cycle progression in G2 phase: arrested | classical genetics | overexpression | S288C | Details: arrest as single, uninuclear cells with bud-like protrusion and 2C DNA content | Booher RN, et al. (1993) PMID:8253069 |