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  • Phenotype: position of spindle pole body: abnormal
  • Overview
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Phenotype: position of spindle pole body: abnormal


Observable
position of spindle pole body
Qualifier
abnormal

Annotations 19 entries for 14 genes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

GenePhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
ATG11position of spindle pole body: abnormal
classical genetics null
Allele: atg11-Δ
S288CTemperature: elevated temperature, 37 °C
Details: 4-fold increase in SPB inheritance defects, with an increased percentage of cells containing daughter SPBs in the mother cell and fewer in the daughter cell, based in Spc42-mCherry signal intensity at 37°C
Reza MH, et al. (2025) PMID:40173187
BUD6position of spindle pole body: abnormal
classical geneticsunspecified
Allele: bud6p-Δ229-549

deletion 229-549; Bim1p interaction region

OtherDetails: inheritance of the old SPB to the bud is decreased by 35%
Ten Hoopen R, et al. (2012) PMID:22608510
CMD1position of spindle pole body: abnormal
classical geneticsconditional
Allele: cmd1-239

F65A, F68A (member of cmd1C group)

OtherOhya Y and Botstein D (1994) PMID:8310294
IRR1position of spindle pole body: abnormal
heterozygous diploidunspecified
Allele: irr1-1

F658G substitution

W303Details: shortened spindles; in 15-20% of cells compared to wt, spindles are both shortened and misoriented
Cena A, et al. (2007) PMID:17229992
KAR9position of spindle pole body: abnormal
classical genetics reduction of function
Allele: kar9-L304P

mutation disrupts interaction with proteins in sumoylation pathway, but retains interactions with spindle positioning proteins

OtherDetails: defect in spindle positioning, spindle located more distally than normal
Meednu N, et al. (2008) PMID:18832349
KAR9position of spindle pole body: abnormal
classical genetics null
Allele: kar9-Δ
S288CDetails: in >90% of wt cells with spindles aligned parallel to the mother-bud axis the newly synthesized SPBs are oriented toward the mother cell side and the old SPBs are oriented toward the bud side, while in the null mutant only 51% of cells orient their old SPB toward the bud side
Hayashida M, et al. (2023) PMID:37918324
KIP3position of spindle pole body: abnormal
classical geneticsnull
Allele: kip3-Δ
OtherDetails: position of the SPB is altered due to excessive growth of astral microtubules at the cortex
Ten Hoopen R, et al. (2012) PMID:22608510
MLP2position of spindle pole body: abnormal
classical geneticsnull
Allele: mlp2-Δ
W303Details: decrease in the average distance between spindle pole bodies compared to wt
Niepel M, et al. (2005) PMID:16027220
RFA1position of spindle pole body: abnormal
classical geneticsoverexpressionS288CDetails: not attached to the nucleus
Niu W, et al. (2008) PMID:18617996
SEC3position of spindle pole body: abnormal
classical geneticsconditional
Allele: sec3-2
OtherTemperature: elevated temperature, 34 °C
Kirchenbauer M and Liakopoulos D (2013) PMID:23447703
Showing 1 to 10 of 19 entries
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