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| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| ATG11 | position of spindle pole body: abnormal | classical genetics | null Allele: atg11-Δ | S288C | Temperature: elevated temperature, 37 °C Details: 4-fold increase in SPB inheritance defects, with an increased percentage of cells containing daughter SPBs in the mother cell and fewer in the daughter cell, based in Spc42-mCherry signal intensity at 37°C | Reza MH, et al. (2025) PMID:40173187 | |
| BUD6 | position of spindle pole body: abnormal | classical genetics | unspecified Allele: bud6p-Δ229-549 deletion 229-549; Bim1p interaction region | Other | Details: inheritance of the old SPB to the bud is decreased by 35% | Ten Hoopen R, et al. (2012) PMID:22608510 | |
| CMD1 | position of spindle pole body: abnormal | classical genetics | conditional Allele: cmd1-239 F65A, F68A (member of cmd1C group) | Other | Ohya Y and Botstein D (1994) PMID:8310294 | ||
| IRR1 | position of spindle pole body: abnormal | heterozygous diploid | unspecified Allele: irr1-1 F658G substitution | W303 | Details: shortened spindles; in 15-20% of cells compared to wt, spindles are both shortened and misoriented | Cena A, et al. (2007) PMID:17229992 | |
| KAR9 | position of spindle pole body: abnormal | classical genetics | reduction of function Allele: kar9-L304P mutation disrupts interaction with proteins in sumoylation pathway, but retains interactions with spindle positioning proteins | Other | Details: defect in spindle positioning, spindle located more distally than normal | Meednu N, et al. (2008) PMID:18832349 | |
| KAR9 | position of spindle pole body: abnormal | classical genetics | null Allele: kar9-Δ | S288C | Details: in >90% of wt cells with spindles aligned parallel to the mother-bud axis the newly synthesized SPBs are oriented toward the mother cell side and the old SPBs are oriented toward the bud side, while in the null mutant only 51% of cells orient their old SPB toward the bud side | Hayashida M, et al. (2023) PMID:37918324 | |
| KIP3 | position of spindle pole body: abnormal | classical genetics | null Allele: kip3-Δ | Other | Details: position of the SPB is altered due to excessive growth of astral microtubules at the cortex | Ten Hoopen R, et al. (2012) PMID:22608510 | |
| MLP2 | position of spindle pole body: abnormal | classical genetics | null Allele: mlp2-Δ | W303 | Details: decrease in the average distance between spindle pole bodies compared to wt | Niepel M, et al. (2005) PMID:16027220 | |
| RFA1 | position of spindle pole body: abnormal | classical genetics | overexpression | S288C | Details: not attached to the nucleus | Niu W, et al. (2008) PMID:18617996 | |
| SEC3 | position of spindle pole body: abnormal | classical genetics | conditional Allele: sec3-2 | Other | Temperature: elevated temperature, 34 °C | Kirchenbauer M and Liakopoulos D (2013) PMID:23447703 |