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| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| CDC45 | chronological lifespan: abnormal | heterozygous diploid | null Allele: cdc45-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| MCM2 | chronological lifespan: abnormal | heterozygous diploid | null Allele: mcm2-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| MCM3 | chronological lifespan: abnormal | heterozygous diploid | null Allele: mcm3-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| MCM4 | chronological lifespan: abnormal | heterozygous diploid | null Allele: mcm4-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| MCM5 | chronological lifespan: abnormal | heterozygous diploid | null Allele: mcm5-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| MCM6 | chronological lifespan: abnormal | heterozygous diploid | null Allele: mcm6-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| MCM7 | chronological lifespan: abnormal | heterozygous diploid | null Allele: mcm7-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| PSF1 | chronological lifespan: abnormal | heterozygous diploid | null Allele: psf1-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| PSF2 | chronological lifespan: abnormal | heterozygous diploid | null Allele: psf2-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 | |
| PSF3 | chronological lifespan: abnormal | heterozygous diploid | null Allele: psf3-Δ | S288C | Details: delayed chronological aging; exhibits delayed senescence during the initial 14 days; incapable of forming colonies beyond 21 days while wt cells remain viable; increased cell size from the onset with declining viability and reduction in ploidy over time | Stępień K, et al. (2024) PMID:37907194 |