Click on a phenotype to go to its specific page within SGD; drag any of the phentoype objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram.
Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Gene | Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|---|
| APC9 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | null Allele: apc9-Δ | S288C | Details: accumulation of G2/M cells | Hall MC, et al. (2003) PMID:12609981 | |
| ASE1 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | overexpression | W303 | Treatment: hydroxyurea block release Details: checkpoint-dependent anaphase entry delay | Liu H, et al. (2008) PMID:19023403 | |
| ASK1 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | conditional Allele: ask1-3 | W303 | Temperature: permissive temperature, 25 °C Treatment: hydroxyurea block release Details: checkpoint-dependent anaphase entry delay | Liu H, et al. (2008) PMID:19023403 | |
| CDC5 | cell cycle passage through the metaphase-anaphase transition: arrested | classical genetics | null Allele: cdc5-S630Q | W303 | Details: alpha-factor arrest at 23C then grown at non-permissive temperature; accumulated large budded cells that failed to divide | Almawi AW, et al. (2020) PMID:32099015 | |
| CIN8 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | overexpression | W303 | Treatment: hydroxyurea block release Details: checkpoint-dependent anaphase entry delay | Liu H, et al. (2008) PMID:19023403 | |
| DOC1 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | null Allele: doc1-Δ | S288C | Details: accumulation of G2/M cells | Hall MC, et al. (2003) PMID:12609981 | |
| IPA1 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | conditional Allele: ipa1-psd photo-sensitive degron (psd) containing allele | S288C | Lutz AP, et al. (2018) PMID:29519818 | ||
| MAD3 | cell cycle passage through the metaphase-anaphase transition: premature | classical genetics | null Allele: mad3-Δ | W303 | 15 µg/ml nocodazole | Treatment: alpha-factor block release Details: synchronized cells treated with nocodazole after SPB separation display a 323 minute decrease in the duration of the spindle checkpoint relative to wt cells based on the time required before separase cleavage of cohesin, assayed using a separase biosensor | MacKenzie A, et al. (2023) PMID:37018287 |
| MND2 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | null Allele: mnd2-Δ | S288C | Details: accumulation of G2/M cells | Hall MC, et al. (2003) PMID:12609981 | |
| RRM3 | cell cycle passage through the metaphase-anaphase transition: delayed | classical genetics | null Allele: rrm3-Δ | S288C | Details: metaphase-anaphase delay based on several observations including cell cycle passage with time-lapse microscopy, an increase in the fraction of cells with a metaphase spindle, stabilization of securin, persistence of the nuclear cohesion pool and delayed release of Cdc14p from the nucleolus | Gordon MR, et al. (2023) PMID:36350688 |