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Gene Ontology Term: GCN2-mediated signaling

GO ID
GO:0140469
Aspect
Biological Process
Description
A series of reactions in which a signal is passed on to downstream proteins within the cell via GCN2 (also known as EIF2AK4), an intracellular protein kinase that is activated by stress signals, such as amino acid starvation.
Synonyms
EIF2AK4-mediated signaling, regulation of eIF2 alpha phosphorylation by amino acid starvation
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Annotations

Manually Curated 6 entries for 4 genes

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Gene/ComplexQualifierGene Ontology TermAnnotation ExtensionEvidenceSourceAssigned OnReference
HEL2acts upstream of or withinGCN2-mediated signalingIDAUniProt2023-02-13Zhu S, et al. (1996) PMID:8798780
GCN2involved inGCN2-mediated signalingIDAUniProt2023-02-13Zhu S, et al. (1996) PMID:8798780
GCN1involved inGCN2-mediated signalingIDAUniProt2023-02-13Yan LL and Zaher HS (2021) PMID:33338396
GCN1acts upstream of or withinGCN2-mediated signalingIDAUniProt2023-02-13Zhu S, et al. (1996) PMID:8798780
MBF1involved inGCN2-mediated signalingIMPSGD2024-12-05Kim KQ, et al. (2024) PMID:39566505
MBF1involved inGCN2-mediated signalingIGI with GCN4SGD2024-12-05Kim KQ, et al. (2024) PMID:39566505
Showing 1 to 6 of 6 entries

High-throughput 0 entries for 0 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Computational 5 entries for 3 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
cellular process (0)