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Gene Ontology Term: ERK5 cascade

GO ID
GO:0070375
Aspect
Biological Process
Description
A MAPK cascade containing at least the ERK5 MAP kinase (MAPK7; also called BMK1). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK5. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The ERK5 cascade is activated by stress, mitogens, and by G protein-coupled receptors, and results in cellular responses such as cell growth, cell differentiation and development.
Synonyms
big MAP kinase signaling cascade, BMK cascade, BMK signaling pathway, BMK signalling pathway, BMK1 cascade, ERK5 signaling pathway, extracellular signal-regulated kinase 5 cascade, MAPK7 cascade
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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

High-throughput

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Computational

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference