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Gene Ontology Term: organelle membrane contact site

GO ID
GO:0044232
Aspect
Cellular Component
Description
A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
Synonyms
inter-organelle junction, interorganelle junction, MCS, interorganelle junction, inter-organelle junction
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Ontology Diagram

Annotations

Manually Curated 3 entries for 3 genes

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Gene/ComplexQualifierGene Ontology TermAnnotation ExtensionEvidenceSourceAssigned OnReference
CNM1is active inorganelle membrane contact sitepart of nuclear envelope, part of mitochondrial outer membraneIDASGD2022-04-08Eisenberg-Bord M, et al. (2021) PMID:34694322
ARF1is active inorganelle membrane contact siteIDASGD2023-07-10Enkler L, et al. (2023) PMID:37400497
VPS13is active inorganelle membrane contact siteIDASGD2022-02-24Park JS, et al. (2016) PMID:27280386
Showing 1 to 3 of 3 entries

High-throughput 0 entries for 0 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Computational 0 entries for 0 genes

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Gene/Complex Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference
cellular component (1385)