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Gene Ontology Term: DNA-binding transcription activator activity, RNA polymerase II-specific

GO ID
GO:0001228
Aspect
Molecular Function
Description
Interacting selectively and non-covalently with a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
Synonyms
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription, distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific, proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding, transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding, transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding, RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding, RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding, RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding, RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding, copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription, metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, transcriptional activator activity, metal ion regulated sequence-specific DNA binding, zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription
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Manually Curated

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Gene Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

High-throughput

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Gene Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference

Computational

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Gene Qualifier Gene Ontology Term Aspect Annotation Extension Evidence Method Source Assigned On Reference