AboutBlogDownloadExploreHelpYeastMine
Email UsTwitterFacebookLinkedinYouTube
Saccharomyces Genome Database
  • Saccharomyces Genome Database
    Saccharomyces Genome Database
  • Menu
  • Analyze
    • Gene Lists
    • BLAST
    • Fungal BLAST
    • GO Term Finder
    • GO Slim Mapper
    • Pattern Matching
    • Design Primers
    • Restriction Site Mapper
  • Sequence
    • Download
    • Genome Browser
    • BLAST
    • Fungal BLAST
    • Gene/Sequence Resources
    • Reference Genome
      • Download Genome
      • Genome Snapshot
      • Chromosome History
      • Systematic Sequencing Table
      • Original Sequence Papers
    • Strains and Species
      • Variant Viewer
      • Align Strain Sequences
    • Resources
      • UniProtKB
      • InterPro (EBI)
      • HomoloGene (NCBI)
      • YGOB (Trinity College)
  • Function
    • Gene Ontology
      • GO Term Finder
      • GO Slim Mapper
      • GO Slim Mapping File
    • Expression
    • Biochemical Pathways
    • Phenotypes
      • Browse All Phenotypes
    • Interactions
    • YeastGFP
    • Resources
      • GO Consortium
      • BioGRID (U. Toronto)
  • Literature
    • Full-text Search
    • New Yeast Papers
    • YeastBook
    • Genome-wide Analysis Papers
    • Resources
      • PubMed (NCBI)
      • PubMed Central (NCBI)
      • Google Scholar
  • Community
    • Colleague Information
      • Find a Colleague
      • Add or Update Info
      • Find a Yeast Lab
    • Career Resources
    • Education
    • Meetings
      • Future
      • Yeast Genetics
    • Nomenclature
      • Submit a Gene Registration
      • Gene Registry
      • Nomenclature Conventions
    • Methods and Reagents
      • Strains and Constructs
      • Reagents
      • Protocols and Methods
    • Historical Data
      • Physical & Genetic Maps
      • Genetic Maps
      • ORFMap Chromosomes
      • Sequence
      • Gene Summary Paragraphs
    • Wiki
    • Submit Data
    • Resources
    • API
  • Info & Downloads
    • About
    • Blog
    • Downloads
    • Site Map
    • Help

    Complex: Anaphase-Promoting complex AMA1 variant

    Macromolecular complex annotations are imported from the Complex Portal. These annotations have been derived from physical molecular interaction evidence extracted from the literature and cross-referenced in the entry, or by curator inference from information on homologs in closely related species or by inference from scientific background.


    Curated by
    IntAct
    ComplexAc
    CPX-762
    Systematic Name
    AMA1:APC1:APC2:APC4:APC5:APC9:APC11:CDC16:CDC23:CDC26:CDC27:DOC1:MND2:SWM1
    Aliases
    APC ; APC-Ama1 ; APC/C ; Anaphase Promoting Complex/Cyclosome ; Anaphase-Promoting Complex ; Cyclosome

    Complex Diagram

    This diagram displays the protein subunits (blue) of the complex and how they interact with each other. Interactions with other relevant participants such as small molecules (purple), sub-complexes (yellow), and other subunits (red) are also shown. If a participant appears in the diagram with no lines connected to it, then its specific interactions with other participants are currently unknown.


    Subunits

    This table lists all participants of the complex (proteins, small molecules, nucleic acids, etc.) and their respective stoichiometry. A brief description is also provided for each participant in the table.


    Increase the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.

    Subunit Description Stoichiometry

    Gene Ontology

    Gene Ontology (GO) terms that describe the function of a complex, the biological process in which it participates, or its cellular location. Click on a term for its definition and other objects annotated to that term.


      Molecular Function
    • ubiquitin protein ligase activity
      Biological Process
    • anaphase-promoting complex-dependent catabolic process
    • protein ubiquitination
    • regulation of meiotic cell cycle
      Cellular Component
    • anaphase-promoting complex

    Shared Annotations

    This diagram displays Gene Ontology terms (green) and subunits (blue) that are shared between the given macromolecular complex (black) and other yeast complexes (yellow). The shared GO terms or subunits can be visualized separately using the radio button at the bottom of the graph. Note: No diagram is shown ("No shared annotations") if there are less than 2 shared annotations (either GO terms or subunits of other complexes) between this complex and any other complexes.


    References

    List of references used specifically to curate the information on this page.


    • Peters JM (2006) The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 7(9): 644-56. PMID: 16896351
      • SGD Paper
      • DOI full text
      • PubMed
    • Castro A, et al. (2005) The anaphase-promoting complex: a key factor in the regulation of cell cycle. Oncogene 24(3): 314-25. PMID: 15678131
      • SGD Paper
      • DOI full text
      • PubMed
    • Oelschlaegel T, et al. (2005) The yeast APC/C subunit Mnd2 prevents premature sister chromatid separation triggered by the meiosis-specific APC/C-Ama1. Cell 120(6):773-88 PMID: 15797379
      • SGD Paper
      • DOI full text
      • PubMed
    • Passmore LA, et al. (2005) Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. Mol Cell 20(6):855-66 PMID: 16364911
      • SGD Paper
      • DOI full text
      • PubMed
    • Townsley FM and Ruderman JV (1998) Proteolytic ratchets that control progression through mitosis. Trends Cell Biol. 8(6):238-44 PMID: 9695848
      • SGD Paper
      • DOI full text
      • PubMed

    External Identifiers


    IntEnz: 6.3.2.19
    • SGD
    • About
    • Blog
    • Help
    • Privacy Policy
    • Creative Commons License
      • Email Us
      • Twitter
      • Facebook
      • LinkedIn
      • YouTube
    © Stanford University, Stanford, CA 94305.
    Back to Top